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Alexander Buko

Alexander Buko

Vice President
Human Metabolome Technologies


Dr. Búko has served as the Vice President of Human Metabolome Technologies-America (HMT-A) Biomarker discovery team since 2013, where he partners with biopharmaceutical companies to bring high resolution quantitative metabolomics profiling to pre-clinical and clinical studies. Prior to joining Human Metabolome Technologies, Dr. Búko was Senior Director Translational Medicine at Biogen for 10 years and Principal Investigator at Abbott labs for 18 years. He received his Ph.D. in Chemistry from the University of Virginia, with post-doctoral work for Bureau of Biologics and Biophysics at Food and Drug administration.

Research Interest

Dr. Búko’s career has focused primarily on omics solutions for biomarker and target discovery within the biopharma pipeline. Most of his work has been in immunology, infectious disease and neurology, however, at HMT-A he has widened his scope to many other therapeutic areas. While in biopharma Alex managed biomarker pipelines from pre-clinical to clinical studies using various protein and small molecule technologies to discovery and validate biomarkers for drug development and patient stratification. Dr. Búko’s areas of expertise include proteomics, lipidomics, metabolomics, protein assays and the statistical and biological pathway approaches required to combine omics data and generate prognostic and diagnostic algorithms.